Molecular mechanisms regulating the spatial configuration of neurites.
Hasegawa K and Kuwako KI
Seminars in Cell and Developmental Biology 129, 103-114 (2022) [Pub Med]

Vascularization of human brain organoids.
Matsui TK, Tsuru Y, Hasegawa K, Kuwako KI
Stem Cells 39(8):1017-1024. (2021) [Pub Med]

Challenges in Modeling Human Neural Circuit Formation via Brain Organoid Technology.
Matsui TK, Tsuru Y, Kuwako KI
Frontiers in Cellular Neuroscience 14, 607399 (2020) [Pub Med]

The polymicrogyria-associated GPR56 promoter preferentially drives gene expression in developing GABAergic neurons in common marmosets.
Murayama AY, Kuwako KI, Okahara J, Byoung-Il Bae, Okuno Y , Mashiko H, Shimogori T, Christopher A Walsh, Sasaki E, Okano H
Scientific Reports 10(1):21516 (2020) [Pub Med]

The LKB1-SIK Pathway Controls Dendrite Self-avoidance in Purkinje Cells. 
Kuwako KI * and Okano H ( * corresponding )
Cell Reports 24, 2808-2818 (2018) [Pub Med]

Versatile Roles of LKB1 Kinase Signaling in Neural Development and Homeostasis.
Kuwako KI * and Okano H ( * corresponding )
Frontiers in Molecular Neuroscience  11, 354 (2018) [Pub Med]

Elavl3 is essential for the maintenance of Purkinje neuron axons. 
Ogawa Y #, Kakumoto K #, Yoshida T, Kuwako KI, Miyazaki T, Yamaguchi J, Konno A, Hata J, Uchiyama Y, Hirai H, Watanabe M, Darnell RB, Okano H, Okano HJ   
Scientific Reports 8, 2722 (2018) [Pub Med]

Cadherin-7 regulates mossy fiber connectivity in the cerebellum. 
Kuwako KI *, Nishimoto Y, Kawase S, Okano HJ, Okano H * ( * corresponding )
Cell Reports 9, 311-323 (2014) [Pub Med]

Regulatory factor X transcription factors control Musashi1 transcription in mouse neural stem/progenitor cells. 
Kawase S, Kuwako K, Imai T, Renault-Mihara F, Yaguchi K, Itohara S, Okano H
Stem Cells and Development 23, 2250-2261 (2014) [Pub Med]

The long non-coding RNA nuclear-enriched abundant transcript 1_2 induces paraspeckle formation in the motor neuron during the early phase of amyotrophic lateral sclerosis. 
Nishimoto Y, Nakagawa S, Hirose T, Okano HJ, Takao M, Shibata S, Suyama S, Kuwako K, Imai T, Murayama S, Suzuki N, Okano H
Molecular Brain 6, 31 (2013) [Pub Med]

Sox21 promotes hippocampal adult neurogenesis via the transcriptional repression of the Hes5 gene. 
Matsuda S #, Kuwako K #, Okano HJ, Tsutsumi S, Aburatani H, Saga Y, Matsuzaki Y, Akaike A, Sugimoto H, Okano H ( # equal first author )
Journal of Neuroscience 32, 12543-12557 (2012) [Pub Med]

Neural RNA-binding protein Musashi1 controls midline crossing of precerebellar neurons through post-transcriptional regulation of Robo3/Rig-1 expression.  
Kuwako K *, Kakumoto K, Imai T, Igarashi M, Hamakubo T, Sakakibara S, Tessier-Lavigne M,  Okano HJ, Okano H *  ( * corresponding )
Neuron 67, 407-421 (2010) [Pub Med]

SOCS3 deletion promotes optic nerve regeneration in vivo.  
Smith PD, Sun F, Park KK, Cai B, Wang C, Kuwako K, Martinez-Carrasco I, Connolly L, He Z
Neuron 64, 617-623 (2009) [Pub Med]

beta1-integrin mediates myelin-associated glycoprotein signaling in neuronal growth cones. 
Goh EL, Young JK, Kuwako K, Tessier-Lavigne M, He Z, Griffin JW, Ming GL  
Molecular Brain 1, 10 (2008) [Pub Med]

Disruption of the paternal necdin gene diminishes TrkA signaling for sensory neuron survival. 
Kuwako K, Hosokawa A, Nishimura I, Uetsuki T, Yamada M, Nada S, Okada M, Yoshikawa K
Journal of Neuroscience 25, 7090-7099 (2005) [Pub Med]

Necdin-related MAGE proteins differentially interact with the E2F1 transcription factor and the p75 neurotrophin receptor.   
Kuwako K, Taniura H, Yoshikawa K
Journal of Biological Chemistry 279, 1703-1712 (2004) [Pub Med]

Gene expression patterns of pro-opiomelanocortin-processing enzymes PC1 and PC2 during postnatal development of rat corticotrophs.  
Kato H, Kuwako K, Suzuki M, Tanaka S
Journal of Histochemistry & Cytochemistry 52, 943-957 (2004) [Pub Med]

Upregulation and antiapoptotic role of endogenous Alzheimer amyloid precursor protein in dorsal root  ganglion neurons.   
Nishimura I, Takazaki R, Kuwako Ki, Enokido Y, Yoshikawa K 
Experimental Cell Research 286, 241-251 (2003) [Pub Med]

Activation of calpain in cultured neurons overexpressing Alzheimer amyloid precursor protein. 
Kuwako K, Nishimura I, Uetsuki T, Saido TC, Yoshikawa K   
Brain Research Molecular Brain Research 107, 166-175 (2002) [Pub Med]

Cell death induced by a caspase-cleaved transmembrane fragment of the Alzheimer amyloid precursor protein.   
Nishimura I, Uetsuki T, Kuwako K, Hara T, Kawakami T, Aimoto S, Yoshikawa K
Cell Death & Differentiation 9, 199-208 (2002)  [Pub Med]